Establishing a diagnosis of GH in a woman who is currently pregnant presents a bit of a challenge since pregnancy alters the thyroid physiology. Women who have Graves' hyperthyroidism should discuss treatment options before they get pregnant if possible, and should know the risks. Photo: rf. For women who opt for surgery or radioactive iodine therapy, the goal should be to achieve a stabilized thyroid hormone replacement dose, optimally for at least 6 months, prior to conception. In a recent study, the authors looked at 2,, completed pregnancies linked to live-born infants over six years, using data from the Korean National Health Insurance database.
Very rarely, antithyroid drugs Normal pregnancy after graves disease cause side effects, including agranulocytosis lowering of the number of white blood cells and severe liver damage. Trophoblastic disease i. Graves' disease can cause problems for you during pregnancy and for your unborn baby's development. During pregnancy, you may need to see fisease endocrinologista doctor who treats people with hormone problems. Fluid balance should be graaves positive. Graves hyperthyroidism and pregnancy: a clinical update. Mandel, S. Patients and Methods. Update on some aspects of neonatal thyroid disease.
Diarrhoea during pregnancy. Explore Everyday Health
With this disease, your immune system makes antibodies that cause the thyroid to make too much thyroid hormone. July 9, at am. Normal pregnancy after graves disease DS, et al. Infertility and thyroid disorders. Testicular function in hyperthyroidism. That means that TRAb overrides the normal regulation of the thyroid, causing an overproduction of thyroid hormones hyperthyroidism. The thyroid enlarges slightly in healthy women during pregnancy, but usually not enough for a health care professional to feel during a physical exam. The improvement in autoimmune thyroid disease during pregnancy and the subsequent exacerbation postpartum is Normal pregnancy after graves disease to immune system changes necessary to a normal pregnancy. Graves' disease resources. Symptoms include.
Graves disease is a condition where the thyroid gland makes too much thyroid hormone.
- Unfortunately, there is no way to monitor or predict the effect on the fetus of any treatment given to the mother.
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- These changes mean that laboratory tests of thyroid function must be interpreted with caution during pregnancy.
Graves disease is a condition where the thyroid gland makes too much thyroid hormone. This is called hyperthyroidism or overactive thyroid. A healthy thyroid gland works normally in pregnancy. The symptoms of hyperthyroidism may look like other health conditions. Always see your healthcare provider for a diagnosis. The healthcare provider will ask about your health history.
He or she will also do a physical exam, and ask about symptoms. Some medicines cross the placenta and may not be safe for the baby. Radioactive iodine damages the overactive thyroid cells. But this treatment is not safe in pregnancy. If you have Graves disease, you can take steps to have a healthy pregnancy.
Get early prenatal care and work with your healthcare provider to manage the disease. Graves disease usually gets worse in the first half of pregnancy. It gets better in the second half, and then gets worse again after delivery. It is important to keep your thyroid levels normal. Hyperthyroidism that is out of control may lead to preterm birth. This is birth before 37 weeks of pregnancy.
It can also lead to low birth weight of the baby. Some pregnant women have a severe life-threatening form of hyperthyroidism called thyroid storm. This is a condition in which there are very high levels of thyroid hormone. Medicines to treat hyperthyroidism may harm your developing baby and newborn. Anti-thyroid medicine may also cause low levels of thyroid hypothyroidism in the developing baby and newborn.
It is usually short-term and does not cause problems for the baby, but careful monitoring is important. At the visit, write down the name of a new diagnosis, and any new medicines, treatments, or tests. Also write down any new instructions your provider gives you. Know why a new medicine or treatment is prescribed, and how it will help you. Also know what the side effects are.
Symptoms include extreme tiredness trouble dealing with cold muscle cramps severe constipation problems with memory or concentration You may have symptoms of hypothyroidism, such as trouble dealing with cold. Marie says:. The thyroid enlarges slightly in healthy women during pregnancy, but usually not enough for a health care professional to feel during a physical exam. If left untreated, damage to the nerves in the eyes can also lead to blindness. Me and my husband would love to start having children.
Normal pregnancy after graves disease. Popular topics
Graves’ hyperthyroidism in pregnancy: a clinical review
But if left untreated, Graves' disease can cause osteoporosis, heart problems, and problems getting pregnant and during pregnancy. Graves' disease is an autoimmune disease that affects the thyroid gland. Your thyroid is a small gland at the base of your neck. Your thyroid gland makes hormones that control many activities in your body, including how fast your heart beats and how fast you burn calories.
Hyperthyroidism causes your metabolism to speed up. Your risk is higher if you: 1. Many of the symptoms of Graves' disease are the same as those of other causes of hyperthyroidism. Other signs are found only in Graves' disease. The symptoms of Graves' disease can start slowly or very suddenly. Some people do not have any symptoms. Graves' disease can lead to an eye problem called Graves' ophthalmopathy. It affects up to half of people with Graves' disease. Graves' ophthalmopathy happens when cells from your body's immune defense system attack the tissues around your eyes.
The result is inflammation and swelling in the eye socket, causing the eyeball to bulge out. If left untreated, damage to the nerves in the eyes can also lead to blindness.
Smoking including secondhand smoke is the leading risk factor for Graves' ophthalmopathy. Quitting smoking lowers your risk for developing Graves' ophthalmopathy. Graves' ophthalmopathy is treated with eye drops and eyeglasses, radiation therapy, or eye surgery.
Your treatment will depend on how serious your eye problems are. Graves' disease is triggered by some process in the body's immune system, which normally protects the body from infection.
In Graves' disease, the body makes an antibody that attacks the cells of the thyroid gland. Graves' disease also affects women differently than men. In addition to causing heart problems and osteoporosis, Graves' disease in women can cause:.
To diagnose Graves' disease, your doctor will do a physical exam and may do some tests. Tests that can help you find out if you have Graves' disease include:. Treatments for Graves' disease lower the amount of thyroid hormone in your body or block the action of thyroid hormone.
There are three main treatments for Graves' disease: 7. Your doctor may also suggest you take a medicine called a beta blocker. Beta blockers block some of the effects of excess thyroid hormone on your body.
They slow down your heart rate and reduce symptoms such as shaking and nervousness. Beta blockers work quickly and can help you feel better while you wait for additional treatment to start working. All medicines have risks. You should talk to your doctor about the benefits and risks of all medicines. Women with Graves' disease often have irregular menstrual periods. If your periods are irregular, you may not ovulate each month, which can make it difficult to get pregnant.
In a man, Graves' disease can harm the sperm, which can make it difficult for you to get pregnant. Treatment of Graves' disease can often make your menstrual periods regular and restore fertility in women and men. Normal hormone changes during pregnancy cause thyroid hormone levels to increase. The thyroid gland may also enlarge slightly in healthy women during pregnancy, but not enough to be felt.
These changes do not affect the pregnancy or your unborn baby. Undiagnosed thyroid gland problems can harm you and your unborn baby. Symptoms of normal pregnancy, such as fatigue and feeling hot, can make it easy to overlook thyroid problems that cause the same symptoms. Tell your doctor or nurse if you have symptoms of overactive thyroid or notice a goiter. During pregnancy, you may need to see an endocrinologist , a doctor who treats people with hormone problems.
Your doctors will check your thyroid levels during pregnancy. You cannot get radioiodine therapy during pregnancy. It can cause problems with your pregnancy and to your unborn baby. Your doctor may give you anti-thyroid medicine instead. Propylthiouracil PTU is safe to take throughout pregnancy. Also, your treatment may change during your pregnancy. For some women with Graves' disease, symptoms are worse in the first trimester and then get better for the rest of the pregnancy as thyroid hormone levels change.
Some women can stop taking anti-thyroid medicines in the last four to eight weeks of pregnancy if their thyroid activity becomes normal. Your doctor will check your thyroid hormone levels again after childbirth. Mothers taking the anti-thyroid drug propylthiouracil PTU can safely breastfeed. Ellen Leschek, M. Niveditha Mohan, M. Department of Health and Human Services.
Citation of the source is appreciated. This content is provided by the Office on Women's Health. Language Assistance Available. Skip to main content. Popular topics Vision and mission Leadership Programs and activities In your community Funding opportunities Internships and jobs View all pages in this section. Subscribe To receive Publications email updates. Graves' disease. Expand all. What is Graves' disease? Who gets Graves' disease? Your risk is higher if you: 1 Have a family history.
Graves' disease may run in families. Researchers are working to find the gene or genes involved. Have another autoimmune disease , such as rheumatoid arthritis, type 1 diabetes , pernicious anemia , or lupus.
Are under stress. Severe emotional stress or trauma may trigger Graves' disease. Recently had a baby. Pregnancy affects the thyroid gland. The risk of developing Graves' disease is seven times higher in the year after giving birth. This suggests that pregnancy might trigger or reveal Graves' disease in some women.
Have a history of infection. Infection may play a role in the development of Graves' disease. Researchers have found a link between Graves' disease and infection with the virus that causes mononucleosis "mono"; Epstein-Barr virus. Smoking raises your risk for Graves' disease.
It is also a leading risk factor for the eye problem seen in Graves' disease, called Graves' ophthalmopathy. What are the symptoms of Graves' disease? What eye problems are caused by Graves' disease? What causes Graves' disease? How does Graves' disease affect women? In addition to causing heart problems and osteoporosis, Graves' disease in women can cause: Problems with your menstrual period.
Your thyroid hormone can affect your menstrual cycle. Too much thyroid hormone can cause irregular menstrual periods and make your periods lighter than normal.
Problems getting pregnant. Irregular menstrual cycles can make it harder for women with Graves' disease to get pregnant. About half of women with Graves' disease have problems getting pregnant.